Am J Hum Genet 92 : — Nat Rev Genet. Single-molecule genome assembly of the basket willow, Salix viminalisreveals earliest stages of sex chromosome expansion. Chromosome-level assembly reveals extensive rearrangement in saker falcon and budgerigar, but not ostrich, genomes.
Sex differences in disease risk from reported genome-wide association study findings. Together, our study provides genome-wide insight into how genetic variation, the X Chromosome, and sex shape human gene regulation and disease.
Benjamin A Sandkam. A model for the evolution of dioecy and gynodioecy. Nature Research menu. Low conservation of gene content in the Drosophila Y chromosome. We found that for the majority of autoimmune diseases, the disease-associated loci exhibit a bias in effect size in one sex Fig.
MLGO: phylogeny reconstruction and ancestral inference from gene-order data. It proves the Mendelian inheritance. The pie chart for a given species represents the adjacency degree of the genes of this species: orange represents genes with no adjacency, light blue genes with adjacency degree of 1 and green genes with adjacency degree of 2.
PDF 37 kb. The probability of g being on the X chromosome is then defined as the frequency of orthologs located onto An. We present a computational method, ADseqwhich, by combining ancestral gene order reconstruction, comparative scaffolding and de novo scaffolding methods, overcomes these two caveats.
Ironside JE. Sequential turnovers of sex chromosomes in African clawed frogs Xenopus suggest some genomic regions are good at sex determination. About this article. Supplementary Information Supplementary Figures 1—